Denatonium Benzoate (Bitrex, Aversion) granules
IUPAC name: Phenylmethyl-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-diethylammonium benzoate
Alternative names: Bitrex; phenylmethyl-[2- [(2,6-dimethylphenyl)amino]- 2-oxoetil]-diethylammonium benzoate; Aversion; Denatonii benzoas; N-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)-N,N-diethylbenzeneme- thanaminium benzoate; Benzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium benzoate; benzyl-[(2,6-dimethylphenyl)carbamoylmethyl]-diethyl-azanium; EPA Pesticide Chemical Code 009106; ((2,6-Xylylcarbamoyl)methyl)diethyl benzyl ammonium benzoate; Benzoato de denatonio; Benzoate de denatonium; Anispray; Lidocaine benzyl benzoate; Benzyldiethyl[(2,6-xylylcarbamoyl)methyl]ammonium benzoate; Benzenemethan-aminium, n-(2-((2,6-dimethylphenyl)amino)-2-oxo-ethyl)-n,n-diethyl-, benzoate; benzyl-[(2,6-dimethylphenyl)carbamoylmethyl]-diethyl-azanium benzoate; Ammonium, benzyldiethyl[ (2,6-xylylcarbamoyl)methyl]-, benzoate; Bitter+Plus
General description of Denatonium Benzoate
Chemical formula: | C21H29N2O • C7H5O2 |
Molar mass: | 446,581 g/mol |
CAS number: | 3734-33-6 |
EC number: | 223-095-2 |
ECHA Infocard: | 100.020.996 |
PubChem: | 19518 |
ChemSpider: | 18392 |
UNII (FDA SRS): | M5BA6GAF1O |

According to Chemistry World, Denatonium Benzoate was an accidental formulation by researchers at T & H Smith in 1958, a Scottish pharmaceutical company that was a precursor for Macfarlan Smith Ltd. The first known application for Denatonium Benzoate was as an aversant for pigs that were cannibalizing their own tails or those of other pigs.
Denatonium Benzoate is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharide. Dilutions of as little as 10 ppm are unbearably bitter to most humans. Denatonium benzoate is used for denaturation of alcohol, in antifreeze, in nail biting preventions, in respirator mask fit-testing, in animal repellents, in liquid soaps and shampoos. It is not known to pose any long-term health risks. When added, it discourages consumption of harmful alcohols like methanol, and additives like ethylene glycol or in rubbing alcohol. It is also added to many kinds of harmful liquids including solvents such as nail polish remover, paints, varnishes, toiletries and other personal care items, and various other household products. Animals are known to have different sensitivities to the effects of denatonium. It is used in some animal repellents (especially for such large mammals as deer). It has been used to safeguard rat poisons from human consumption, as humans are able to detect denatonium at much lower concentrations than rodents.
Denatonium Benzoate is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharide. Dilutions of as little as 10 ppm are unbearably bitter to most humans. Denatonium benzoate is used for denaturation of alcohol, in antifreeze, in nail biting preventions, in respirator mask fit-testing, in animal repellents, in liquid soaps and shampoos. It is not known to pose any long-term health risks. When added, it discourages consumption of harmful alcohols like methanol, and additives like ethylene glycol or in rubbing alcohol. It is also added to many kinds of harmful liquids including solvents such as nail polish remover, paints, varnishes, toiletries and other personal care items, and various other household products. Animals are known to have different sensitivities to the effects of denatonium. It is used in some animal repellents (especially for such large mammals as deer). It has been used to safeguard rat poisons from human consumption, as humans are able to detect denatonium at much lower concentrations than rodents.
Product description


The fine particles of the product may easily been taken with the air which makes not only the handling person but also the people in the environment tasting the very bitter taste. Therefore a good product has low powder content. The bitter taste is sensible even 500 meters from the place of handling in case of a dusting product. Our product is a dust-free granulate that makes easier and safer to hanle than most of the grades available in the market.
We deliver this product in a recloseable polyethylene bottle, a polyamide bag inside tightly closed containing the product. Therefore the remaining product can be well stored after taking out a part of it.
We deliver this product in a recloseable polyethylene bottle, a polyamide bag inside tightly closed containing the product. Therefore the remaining product can be well stored after taking out a part of it.
Specification

Property | specification | unit of measure |
---|---|---|
Appearance | White odourless granules | |
Purity | ≥ 99,0 | % (m/m) |
pH | 6,5 - 7,5 | |
Chloride content | ≤ 0,2 | % (m/m) |
Drying loss | ≤ 1,0 | % (m/m) |
Sulfate ash content | ≤ 0,1 | % (m/m) |
Loss on ignition | ≤ 0,1 | % (m/m) |
Melting point | 163 - 170 | °C |
Granulation | diameter: 1,0-1,5; length: 1-5 | mm |
Solubility data %(m/v)
Solvent | at 37°C | at 20°C | at 2°C |
---|---|---|---|
Víz | 7.15 | 4.50 | 3.60 |
Metanol | 69.20 | 68.90 | 62.10 |
Etanol | 35.40 | 35.50 | 35.70 |
Izopropanol | 10.60 | 10.50 | 5.20 |
Butanol | 22.20 | 20.80 | 16.40 |
Aceton | 1.95 | 1.40 | 0.90 |
Benzol | 1.55 | 1.15 | 0.51 |
Metil-etil keton | 0.50 | 0.49 | 0.60 |
Kloroform | 42.80 | 33.00 | 18.50 |
Dietil-éter | -- | 0.015 | 0.01 |
Etil-acetát | 0.30 | 0.25 | 0.12 |
Application areas of Denatonium Benzoate
Car chemicals | Household products | Garden and plant protection | Cosmetics | Fragrances |
---|---|---|---|---|
Antifreeze
Windshield washer Car cleaners Car polishes Degreasers Brake fluids Air fresheners |
Kitchen cleaners
Bathroom cleaners Liquid detergents Fabric softeners Stain removers Glass cleaners |
Rodent killers
Slug & snail baits Liquid fertilizers Herbicides Insecticides Wild animal repellents |
Nail polish removers
Hand sanitizers Hair dyes |
Candles
Liquid pot-pourri |
Safety
Classification in accordance with Regulation (EU-GHS/CLP) No 1272/2008
Acute toxicity (ingestion, inhalation) | Category 4 |
Serious eye damage/irritation | Category 1 |
Classification in accordance with Regulations 67/548/EC or 1999/45/EC
Xn, Harmful | R20 Harmful by inhalation. |
Xi, Irritative | R36/37/38 Irritating to eyes, respiratory system and skin. |
Labelling


Warning
H302 | Harmful if swallowed. |
H318 | Causes serious eye damage. |
H332 | Harmful if inhaled. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P264 | Wash hands thoroughly after handling. |
P305+P351+P338 | IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. |
Information regarding delivery
The product is not classified as dangerous from delivery (ADR) regulations point of view.
Other information
Customs tariff Nr.: 2924297099
Article Nr.: 93823824 (10 x 1 kg/ carton box)
Article Nr.: 93823033 (1 kg/bottle)
Article Nr.: 93823211 (25 kg/drum)
Article Nr.: 93823824 (10 x 1 kg/ carton box)
Article Nr.: 93823033 (1 kg/bottle)
Article Nr.: 93823211 (25 kg/drum)
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In case you already purchased from us, please send us an e-mail by clicking on the 'Order' button here below.
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